SPP 2332 – Physics of Parasitism

The priority programme “Physics of Parasitism” defines a new frontier in this field, namely the physics of parasites interacting with their hosts. “We ultimately aim to elaborate a comparative and quantitative framework of the physical constraints and mechanical forces acting at the dynamic parasite-host interfaces. We will measure the material properties and mechanics of parasites in their niches, uncover the physical basis of their locomotion, and determine the mechanical and physical basis for their attachment.” The priority programme uniquely combines expertise from parasitology, molecular cell biology, experimental and theoretical physics, mathematics and simulation science.

The DRFZ is involved with the following projects:

Locomotion of parasitic nematodes in the gut: movement in viscoelastic mucus intertwined with the metabolic activity of the nematodes (Raluca Niesner in collaboration with Susanne Hartmann, FU Berlin)

Physical principles of parasite-host interactions in Giardia muris infection (Anja Hauser in collaboration with Sebastian Rausch, FU Berlin)