ERC starting grant: iMOTIONS

ERC Grants

Intestinal fibrosis is a common and serious complication of inflammatory bowel disease (IBD). To date, no specific medicine can yet prevent or reverse intestinal fibrosis. The aim of the project “Interaction between the immune system and stroma in inflammation and fibrosis: using the spatio-temporal dynamics of the OSM-OSMR axis in inflammatory bowel disease to develop new antifibrotic therapies”  (iMOTIONS)  is to gain a molecular understanding of the disturbed cell communication in the intestine, define novel biomarkers to identify patients at risk of developing intestinal fibrosis and provide the means to prevent and treat fibrotic disease.