ERC Advanced Grant ILCADAPT: How cells of the innate immune system respond to tissue metabolic changes

ERC Grants

In the project “ILCADAPT: How cells of the innate immune system respond to tissue metabolic changes“, it is investigated how innate immune cells change during pregnancy and thereafter. Andreas Diefenbach’s research group was able to show that these lymphocytes control the uptake of nutrients, such as lipids and carbohydrates, by epithelial cells of the intestine, and thus adapt the organism to the increased nutritional requirements during pregnancy. How this interaction between lymphocytes and intestinal epithelial cells exactly works will now be studied with the support of this ERC grant. This could lead to new approaches for the treatment of metabolic diseases.